Improved Oxymorphone Detection in Postmortem Specimens
نویسندگان
چکیده
منابع مشابه
Interpretation of Ethanol Analysis in Postmortem Specimens
Since alcohol is a general central nervous system depressant, it affects the motor and cognitive performance. Alcohol abuse is a major cause of medical and social problems. Additionally, to determine cause of death in legal medicine centers, alcohol analysis is the most frequently performed test in forensic toxicology laboratories. Accurate interpretation of ethanol concentration at the time...
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Oxymorphone, a semi-synthetic opioid analgesic, has been available as Numorphan since the 1950s in the form of injectable solutions and a suppository. Recently, in 2006, oxymorphone was approved by the Federal Drug Administration for use in the form of immediate and extended release tablets under the trade name Opana. Since the advent of Opana, the number of deaths involving oxymorphone has ris...
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A 78-year-old woman was found dead in her basement. Qualitative screening of available postmortem specimens detected the presence of diltiazem and pentoxifylline. Quantitations were carried out by gas chromatography using nitrogen-phosphorus detection and confirmed by gas chromatography-mass spectrometry with the following results: blood, 0.59 mg/dL diltiazem and 0.63 mg/dL pentoxifylline; urin...
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Opiate testing is one of the most frequently requested assays in the death investigation of suspected drug overdoses. Screening assays typically target morphine, whereas more specific assays are able to positively identify and quantitate the particular opiate present in the specimen. Because many opiates are metabolized to morphine, it is often desirable to differentiate heroin-related deaths f...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2010
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/34.2.112